Timmy Turner's Tragedy follows the main protagonist, Timmy Turner along with his fairies, Cosmo, Wanda, and Poof as they are forced to deal with the L.O.S.E.R.S. who had just got together with everyone single one of their enemies. Because this story shows Timmy's world being taken over, it will take place during the Universal Takeover Saga.
The story starts out with Timmy Turner waking up on a Friday thinking its going to be best day of the week. That is until one by one, his enemies start making his day worse and worse. This continues until Timmy snaps and wishes them all away. But this was part of their plan to recuet all of his enemies.