Syndrome is arch nemesis of Mr.Incredible and also Organization's top scientist that were involved with the Antihero project
Syndrome's personality describes him as a person with complete lack of conscience, a direct result of psychopathy, making him a mad scientist. Intensely amoral, he allowed missiles that he shot at an airplane carrying Helen, Dash, and Violet to continue on after Helen revealed the children's presence on the plane, and even bet Mirage's life in a subsequent showdown when Mr. Incredible threatened her, showing him as a completely amoral person without any regard for human life. Furthermore, he is depicted as a frustrated and spiteful character. Indeed, as a young Buddy Pine, he aspires to become a famous superhero. This goal led him to beg Bob Parr to hire him as a sidekick. But after Bob categorycally refused to grant Buddy's favour, the future Syndrome has developed much rancor for not being admired as much as his model by him and by the people. This obstacle and the lack of real superpower gave him the will of overcoming superheroes, until aspiring to eliminate them, in order to become a popular and "self-made" hero.
Syndrome was one of the few responsible for the machine for Antihero and still working to threwout few bugs, still harbour a grudge against Mr.Incredibles